In this episode, Kenneth Shinozuka discusses his transition from Alzheimer’s research at Harvard to consciousness and psychedelics research at Oxford. In the first half, Kenneth shares insights on Alzheimer’s, consciousness, and the power of music within the deteriorating brain. For the second half, we dive into his research on psychedelics and brain hierarchy, discussing his work on directedness of information flow as well as several related topics like entropy, connectome harmonics, desynchronization, and more. Finally, Kenneth shares an insightful perspective on the medicalization of psychedelics, discussing the role of neuroscience in optimizing treatment decisions as well as the importance of having a cultural matrix within which the drug is embedded.